{
  "id": "gir",
  "version": "7d90ea33152b",
  "status": "published",
  "name": "GIR Calculator",
  "question": "What is the GIR?",
  "summary": "Works out the glucose infusion rate (GIR) in mg/kg/min from the dextrose concentration, the infusion rate in mL per hour, and the weight, with the fluid volume in mL/kg/day.",
  "category": "health",
  "subcategory": "clinical",
  "url": "https://www.acalculator.org/health/gir-calculator",
  "markdown": "https://www.acalculator.org/health/gir-calculator.md",
  "kind": "function",
  "method": "GIR (mg/kg/min) = dextrose % × rate (mL/h) × 10 ÷ (60 × weight in kg) = % × mL/h ÷ (6 × kg).",
  "assumptions": [
    "Dextrose % means grams per 100 mL, so 1% is 10 mg per mL.",
    "Only the dextrose fluid counts. Glucose from feeds or other lines is not added.",
    "The page shows the arithmetic for a prescribed infusion. It does not choose a dextrose strength or a rate."
  ],
  "inputs": {
    "$schema": "https://json-schema.org/draft/2020-12/schema",
    "type": "object",
    "properties": {
      "dextrose": {
        "title": "Dextrose concentration",
        "description": "The dextrose in the fluid, in grams per 100 mL (D10 is 10%), from 1% to 70%.",
        "type": "number",
        "x-unit": "percent",
        "minimum": 1,
        "maximum": 70
      },
      "rate": {
        "title": "Infusion rate (mL/h)",
        "description": "The pump rate of the dextrose fluid, in mL per hour, from 0.1 to 500.",
        "type": "number",
        "minimum": 0.1,
        "maximum": 500
      },
      "weight": {
        "title": "Weight",
        "description": "Body weight, from 300 g to 200 kg.",
        "type": [
          "number",
          "string"
        ],
        "x-quantity": "mass",
        "minimum": 0.3,
        "maximum": 200
      }
    }
  },
  "outputs": {
    "gir": {
      "label": "GIR (mg/kg/min)",
      "description": "Dextrose % × mL/h × 10 ÷ (60 × kg), to 2 decimals.",
      "format": "number"
    },
    "glucose": {
      "label": "Glucose per day (g/kg/day)",
      "description": "The same glucose per day: GIR × 1,440 minutes ÷ 1,000, to 2 decimals.",
      "format": "number"
    },
    "fluid": {
      "label": "Fluid (mL/kg/day)",
      "description": "The fluid this infusion gives: mL/h × 24 ÷ kg, to 1 decimal.",
      "format": "number"
    }
  },
  "defaultAnswer": {
    "inputs": {
      "dextrose": 10,
      "rate": 10,
      "weight": "3.5 kg"
    },
    "outputs": {
      "gir": 4.761904761904762,
      "glucose": 6.857142857142857,
      "fluid": 68.57142857142857
    },
    "text": "10% dextrose at 10 mL/h for 3.5 kg gives a glucose infusion rate of 4.76 mg/kg/min."
  },
  "examples": [
    {
      "given": {
        "dextrose": 10,
        "rate": 10,
        "weight": 3.5
      },
      "expect": {
        "gir": 4.761904761904762,
        "glucose": 6.857142857142857,
        "fluid": 68.57142857142857
      },
      "source": "Solimano 2020: GIR = % × mL/h ÷ (6 × kg) = 100 ÷ 21 = 4.76 mg/kg/min (hand calculation in content.mdx)"
    },
    {
      "given": {
        "dextrose": 10,
        "rate": 12,
        "weight": 3
      },
      "expect": {
        "gir": 6.666666666666667,
        "glucose": 9.6,
        "fluid": 96
      },
      "source": "10 × 12 ÷ (6 × 3) = 6.67 mg/kg/min; 12 × 24 ÷ 3 = 96 mL/kg/day (hand calculation in content.mdx)"
    },
    {
      "given": {
        "dextrose": 12.5,
        "rate": 6,
        "weight": 1.25
      },
      "expect": {
        "gir": 10,
        "glucose": 14.4,
        "fluid": 115.2
      },
      "source": "12.5 × 6 ÷ (6 × 1.25) = 10 mg/kg/min; 6 × 24 ÷ 1.25 = 115.2 mL/kg/day (hand calculation in content.mdx)"
    },
    {
      "given": {
        "dextrose": 5,
        "rate": 9,
        "weight": 1.5
      },
      "expect": {
        "gir": 5,
        "glucose": 7.2,
        "fluid": 144
      },
      "source": "5 × 9 ÷ (6 × 1.5) = 5 mg/kg/min (hand calculation in content.mdx)"
    }
  ],
  "sources": [
    "Solimano A. Drop that calculator! You can easily calculate the glucose infusion rate in your head, and should! Paediatr Child Health. 2020;25(4):199-200. https://doi.org/10.1093/pch/pxz115 (open at https://pmc.ncbi.nlm.nih.gov/articles/PMC7286731/, retrieved 2026-10-05)",
    "Kiyohara AP, Wada RM, Kling ER. Neonatal Hypoglycemia. Case Based Pediatrics for Medical Students and Residents, University of Hawaii. https://www.hawaii.edu/medicine/pediatrics/pedtext/s03c08.html (retrieved 2026-10-05)"
  ],
  "related": [],
  "changelog": [
    {
      "date": "2026-10-05",
      "note": "Published after this site's editorial review against the cited sources (no clinician review); the page notices say so."
    }
  ]
}
